Define Ventures

VC firm · San Francisco, CA

SEC-registered adviser

Venture firm based in San Francisco, CA. Most recent fund on file: Define Ventures Select I, L.P. ($6.2M offering), filed Feb 2024. Partners sit on the boards of 2 startups that raised recently.

“Define Ventures is one of the largest funds focused on early-stage digital health companies. Our founders choose us because we play offense and drive results.” (from the firm’s website)

Stages: Seed to Series B
Typical check (est.): $50K–$200K
Latest fund: $6.2M · Feb 2024
Last verified activity: Apr 2025

Focus

Healthcare

Recent portfolio activity

Layer Health
Board seat · MA
Apr 2025
Soda Health
Board seat · IL
May 2024

Funds and vehicles on SEC file

Define Ventures Select I, L.P.
Fund · $6.2M offering
Feb 2024

Sources

SEC Form D: Define Ventures Select I, L.P.Feb 22, 2024
SEC adviser record: Define Ventures Management, LLCMar 27, 2026
Firm websiteOct 12, 2026

Profile last verified Oct 12, 2026. Is this you? Correct or remove this profile.