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Startup investors in Boston

115 investors based in Boston filed a new fund, deal vehicle or board seat with the SEC in the last 12 months, 32 (28%) of them in the last 90 days. The most common sectors are Healthcare (17), AI & ML (14) and Biotech & Pharma (14). For the 73 with a stated or estimated check size, the median range is $950K–$2.85M. Counted by the office address on their SEC filings; many invest well beyond Boston.

Updated from SEC filings · How we build this list

Who are the most active startup investors in Boston?

By new SEC filings in the last 12 months, the most active are GC Venture, Spark Capital, J2 Ventures Strategic, Anchor Capital and Engine.

How many startup investors in Boston are investing right now?

115 filed a new fund, deal vehicle or board seat with the SEC in the last 12 months, 32 of them in the last 90 days.

How much do startup investors in Boston typically invest?

The median estimated check is $950K–$2.85M, across 73 investors with a plausible estimate. Actual checks vary by round and lead role.

What sectors do startup investors in Boston back most?

Healthcare (17), AI & ML (14) and Biotech & Pharma (14) lead, by investors with recent activity in each.

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  • GC VentureVC firm · Cambridge, MA

    Seed, Series A · checks $800K–$2.45M (est.)

    Sector focus not yet verified

  • Spark CapitalVC firm · Boston, MA

    Seed to Growth

    AI & ML

  • J2 Ventures StrategicVC firm · Boston, MA

    Seed, Series A · checks $125K–$350K (est.)

    AI & MLDeveloper ToolsCybersecurityGovTech & Public Sector

  • Anchor CapitalSyndicate · Boston, MA

    Pre-seed to Series A · checks $350K–$2.6M (est.)

    Industrial & Manufacturing

  • EngineVC firm · Cambridge, MA

    Seed to Series B · checks $5M–$15M (est.)

    Climate & EnergyAI & MLIndustrial & ManufacturingSpace

  • Azolla VenturesVC firm · Cambridge, MA

    Seed, Series A · checks $1.5M–$4.5M (est.)

    Climate & EnergyB2B Software

  • AV FoundationVC firm · Boston, MA

    Seed, Series A

    Sector focus not yet verified

  • Polaris PartnersVC firm · Boston, MA

    Seed to Growth · checks $5M–$15M (est.)

    Biotech & PharmaHealthcareMedia, Gaming & CreatorFintech+1

  • Founder CollectiveSyndicate · Cambridge, MA

    Pre-seed to Series A · checks $950K–$2.85M (est.)

    Healthcare

  • Channel PointSyndicate · Boston, MA

    Pre-seed, Seed · checks $350K–$700K (est.)

    Sector focus not yet verified

  • Third Rock VenturesVC firm · Boston, MA

    Series A to Growth · checks $7.5M–$22.5M (est.)

    Biotech & PharmaHealthcare

  • AltimeterVC firm · Boston, MA

    Seed, Series A · checks $1M–$3M (est.)

    Sector focus not yet verified

  • HLM VMVC firm · Waltham, MA

    Seed, Series A · checks $625K–$1.85M (est.)

    Healthcare

  • Atlas VentureVC firm · Boston, MA

    Series B, Growth · checks $4M–$12M (est.)

    Biotech & Pharma

  • Transformation CapitalVC firm · Boston, MA

    Pre-seed, Series B · checks $150K–$450K (est.)

    HealthcareClimate & Energy

  • FH Venture PartnersVC firm · Boston, MA

    Seed, Series A

    Biotech & Pharma

  • Safar PartnersVC firm · Cambridge, MA

    Seed to Series B · checks $3M–$9M (est.)

    HealthcareAI & MLIndustrial & ManufacturingClimate & Energy

  • 021T CapitalVC firm · Cambridge, MA

    Seed, Series A · checks $1M–$3M (est.)

    Sector focus not yet verified

  • E14Syndicate · Cambridge, MA

    Pre-seed to Series A · checks $500K–$3.55M (est.)

    Hardware & RoboticsAI & MLDeep TechB2B Software+1

  • Breakthrough Energy VenturesVC firm · Boston, MA

    Seed, Series A · checks $1M–$3M (est.)

    Climate & Energy

  • Elephant PartnersVC firm · Boston, MA

    Series A to Growth · checks $7M–$21M (est.)

    B2B SoftwareE-commerce & RetailConsumer

  • Branch Venture PartnersVC firm · Boston, MA

    Seed, Series A

    Sector focus not yet verified

  • Altimeter KilaueaVC firm · Boston, MA

    Pre-seed, Seed · checks $400K–$1.2M (est.)

    Sector focus not yet verified

  • CafeVC firm · Boston, MA

    Pre-seed, Seed · checks $400K–$1.2M (est.)

    Sector focus not yet verified

  • Indicator VenturesVC firm · Wellesley, MA

    Seed · checks $725K–$2.15M (est.)

    FintechHealthcareE-commerce & Retail

  • Skeleton Key SciTechVC firm · Boston, MA

    Pre-seed, Seed · checks $75K–$250K (est.)

    Sector focus not yet verified

  • Altimeter Premier GrowthVC firm · Boston, MA

    Series B, Growth · checks $15.6M–$46.6M (est.)

    Sector focus not yet verified

  • RaptorVC firm · Boston, MA

    Pre-seed, Seed · checks $50K–$150K (est.)

    ConsumerDeep TechReal Estate & PropTechMedia, Gaming & Creator

  • OffscriptSyndicate · Boston, MA

    Pre-seed, Seed · checks $7.7M–$15.4M (est.)

    Sector focus not yet verified

  • Ot HealthcareVC firm · Boston, MA

    Pre-seed, Seed · checks $25K–$100K (est.)

    Healthcare

  • 2026 FAN PierVC firm · Boston, MA

    Seed, Series A

    Sector focus not yet verified

  • Milemark AptaminoVC firm · Cambridge, MA

    Seed, Series A

    Sector focus not yet verified

  • C10 LabsSyndicate · Cambridge, MA

    Pre-seed, Seed · checks $150K–$300K (est.)

    AI & MLDeep Tech

  • Fidelity VentureVC firm · Boston, MA

    Pre-seed, Seed · checks $250K–$750K (est.)

    Sector focus not yet verified

  • LRVHealthVC firm · Boston, MA

    Seed to Series B · checks $2M–$6M (est.)

    Healthcare

  • Castle Island VenturesVC firm · Boston, MA

    Seed, Series A · checks $1.68M–$5.05M (est.)

    FintechB2B SoftwareHealthcare

  • GC Venture XIII ArrangerVC firm · Cambridge, MA

    Seed, Series A

    Sector focus not yet verified

  • Altimeter CatskillVC firm · Boston, MA

    Pre-seed, Seed · checks $250K–$750K (est.)

    Sector focus not yet verified

  • AV HealthtechVC firm · Boston, MA

    Seed, Series A

    Sector focus not yet verified

  • Alaris VenturesVC firm · Boston, MA

    Seed, Series A

    Sector focus not yet verified