645 Ventures

VC firm · New York, NY

SEC-registered adviser

Venture firm based in New York, NY. Most recent fund on file: 645 Ventures Select I, L.P. ($153M offering), filed Jun 2023. Partners sit on the boards of 5 startups that raised recently.

“645 Ventures is an early-stage venture capital firm backing exceptional founders across Enterprise, Deep Tech, AI Infrastructure, Fintech, Consumer, Cybersecurity, and Health Tech.” (from the firm’s website)

Stages: Seed to Growth
Typical check (est.): $1M–$5M
Latest fund: $153M · Jun 2023
Last verified activity: Apr 2024

Focus

Deep TechHealthcareConsumerDeveloper Tools

Recent portfolio activity

Clerq
Board seat · NY
Apr 2024
Setpoint Technologies
Board seat · TX
Mar 2024
Vividly
Board seat · TX
Feb 2024
ReflexAI
Board seat · NY
Mar 2023
Efficient Capital Labs
Board seat · NY
Jan 2023

Funds and vehicles on SEC file

645 Ventures Select I, L.P.
Fund · $153M offering
Jun 2023
645 Ventures IV, L.P.
Fund · $194M offering
Jun 2023

Sources

SEC Form D: 645 Ventures Select I, L.P.Jun 13, 2023
SEC Form D: 645 Ventures IV, L.P.Jun 13, 2023
SEC adviser record: 645 Ventures Management, LLCMar 31, 2026
Firm websiteOct 12, 2026

Profile last verified Oct 12, 2026. Is this you? Correct or remove this profile.